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Abstract #2901

Comparison of a short-TE whole brain MR spectroscopic imaging to single voxel spectroscopy for measurement of metabolite concentrations in human brain

Xiao-Qi Ding 1 , Andrew A. Maudsley 2 , Mohammad Sabati 2 , Sulaiman Sheriff 2 , and Heinrich Lanfermann 1

1 Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Lower Saxony, Germany, 2 Department of Radiology, University of Miami School of Medicine, FL, United States

A short TE whole brain MR spectroscopic imaging (wbMRSI) for detection of focal metabolite concentrations in human brain within a clinically acceptable scan time has been evaluated. Twenty healthy volunteers were scanned both with wbMRSI and Single-Voxel Spectroscopy (SVS), and the measurements compared. The results showed that short TE wbMRSI could be used to estimate focal concentrations of NAA, Cho, tCr, mI, and Glx as well as those with SVS, with additional advantages that metabolite concentrations could be evaluated at more brain regions.

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