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Abstract #2902

Manipulator-mounted optical/NMR dual-modality probe for multimodality scanning in MR guided and robot-assisted interventions

Junmo An 1 , Ahmet E. Sonmez 1 , Mahmut Unan 1 , Robert D. Darrow 2 , Ileana Hancu 2 , R. Jason Stafford 3 , Andrew G. Webb 4 , and Nikolaos V. Tsekos 1

1 University of Houston, Houston, Texas, United States, 2 GE Global Research Center, New York, United States, 3 University of Texas MD Anderson Cancer Center, Texas, United States, 4 Leiden University, Leiden, Netherlands

The aim of this work is to implement a dual modality optical/NMR probe for intraoperative loco-regional and spatially co-registered collection on light-induced fluorescence and NMR spectra. The multi-fiber optical sensor that functions as an emitter and receiver is surrounded by a solenoid microcoil for 1H spectroscopy or MR imaging. The probe is mounted on an MR compatible manipulator for intraoperative biosensing in situ and mechanical scanning to map the spatial distribution of optical/NMR signal sources. Testing was conducted on a multi-compartment phantom of fluorophores and metabolites demonstrated the MR compatibility of the device and the spatial matching of the distribution of optical and MR signal sources.

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