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Abstract #3050

A New Approach to Functional and Structural Connectivity in Human Brain Based on Anisotropic Correlations in Resting State MRI

Zhaohua Ding 1,2 , Ran Xu 1 , Victoria L Morgan 1,3 , Adam W Anderson 1,3 , and John C Gore 1,3

1 Vanderbilt University Institute of Imaging Science, Nashville, TN, United States, 2 Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, United States, 3 Biomedical Engieering, Vanderbilt University, Nashville, TN, United States

Synopsis: Resting state functional magnetic resonance imaging (MRI) has been conventionally used to study functional connectivity between cortical regions. We present here a novel technique that may be used to depict functional pathways of the human brain. A key concept proposed is spatio-temporal correlation tensor, which is constructed on the basis of spatio-temporal analyses of resting state MRI signals. Our in vivo experiments demonstrate that the technique holds a great potential of directly mapping structure-function relations in the human brain.

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