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Abstract #3123

Characterization of Intrinsic Susceptibility Gradients Using R 1 Dispersion

John Thomas Spear 1,2 and John C. Gore 2,3

1 Physics & Astronomy, Vanderbilt University, Nashville, TN, United States, 2 Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, 3 Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

Diffusion of water through susceptibility gradients causes R 1 lower case Greek rho dispersion to a degree that depends on the geometry and size of the inhomogeneities responsible for the gradients. Finite difference simulations were run and compared to experimental data to further substantiate a method to quantify the spatial scales of packed inhomogeneities that has been presented in the literature. R 1 lower case Greek rho dispersions were simulated for spherical and cylindrical structures with varying radii and volume fractions to estimate the correlation time, a parameter that estimates the scale of the gradients.

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