Abstract #3200
Optimizing single component DESPOT using a Cramer-Rao Lower Bound framework
Rui Pedro A. G. Teixeira 1,2 , Shaihan J. Malik 1,3 , and Joseph V. Hajnal 1,3
1
Division of Imaging Sciences and Biomedical
Engineering, King's College London, London, London,
United Kingdom,
2
Institute
of Biophysics and Biomedical Engineering, Faculty of
Sciences, Lisbon, Lisbon, Portugal,
3
Centre
for the Developing Brain, King's College London, London,
London, United Kingdom
The Driven Equilibrium Single Pulse Observation of T1 &
T2 (DESPOT) relaxometry technique aims to provide high
quality 3D maps of T1 and T2 within a clinical time
frame. We propose an optimization method built on the
Cramr-Rao Lower Bound to guarantee low estimation
standard deviation over a defined range of relaxation
times and use it to design optimal single compartment
DESPOT acquisitions for adult and neonatal brain.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
