Abstract #3222
Thermal Responses of MRI Contrasts in ex vivo Tumor and Muscle Tissue
Matthew Tarasek 1 , Oguz Akin 2 , Jeannette Roberts 3 , Thomas Foo 1 , and Desmond Yeo 1
1
Diagnostics & Biomedical Technologies, GE
Global Research, Niskayuna, NY, United States,
2
Radiology,
Memorial Sloan Kettering Cancer Center, NY, United
States,
3
Biomedical
Imaging & Physiology, GE Global Research, Niskayuna, NY,
United States
Longitudinal relaxation time (T1), and transverse
relaxation time (T2) are examples of imaging parameters
that change with temperature. It is challenging to use
these descriptors to measure temperature in vivo because
the way they change is very tissue dependant. Here we
use T1, and T2 to determine salient characteristics of
ex vivo rat breast adenocarcinoma and rat prostate
carcinoma tumors and their surrounding muscle tissues at
steady-state temperatures from ~0C to 22C. Findings
indicate a link to improved MR imaging visualization or
characterization of tumors with heat-induced T1/T2
relaxation contrast types.
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