Transverse Relaxometry for Brain Iron: Comparison of Seven Approaches
Md Nasir Uddin 1 , R Marc Lebel 1,2 , and Alan H Wilman 1
Biomedical Engineering, University of
Alberta, Edmonton, Alberta, Canada,
Science Laboratory, GE Healthcare, Calgary, Alberta,
Quantitative transverse relaxation measurements and the
low and field strengths difference measures can be used
to assess iron levels in the human brain. We compared
the R2, R2*, R2 and multi-slice FDRI mapping approaches
for iron sensitivity measurements in deep gray matter
using 1.5 T and 4.7 T. Results show R2* is most
sensitive at iron at high field while R2 and FDRI
provide specific brain iron measures.
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