Cerebral abnormalities in the gray matter volumes and metabolite concentration in patients with generalized anxiety disorder: voxel-based mormphometry and 1H-MRS
Chung-Man Moon 1 and Gwang-Woo Jeong 1,2
Interdisciplinary Program of Biomedical
Engineering, Chonnam National University, Gwangju,
Chonnam National University Hospital, Gwangju, Korea
Patients with generalized anxiety disorder (GAD) suffer
the symptoms of psychological distress including
excessive and uncontrollable anxiety about everyday
things. These symptoms are assumed to be related with
neural dysfunction or malfunction. The purpose of this
study was to investigate cerebral abnormalities in the
overall gray matter (GM) volumes and metabolite
concentration in patients with GAD using the voxel-based
morphometry (VBM) and localized 1H-MR spectroscopy (MRS).
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