High resolution anatomical and T1/T2 relaxometry maps of the human eye in a clinically-feasible protocol
Laura Fanea 1 , James F Meaney 2 , and Andrew J Fagan 2
Radiology, Cluj County Emergency Hospital,
Cluj-Napoca, Cluj, Romania,
Centre for Advanced Medical Imaging, St. Jamess
Hospital / School of Medicine, Trinity College
University of Dublin, Dublin, Ireland
A clinically-feasible protocol for acquiring high
spatial resolution anatomical and relaxometry maps of
the eye is presented and demonstrated on a volunteer
cohort. Images showing three distinct retinal layers
with thicknesses approaching 610 m were routinely
obtained, with normative retinal layer thicknesses
showing significantly thinner outer layers. Further,
normative T1 values were established in eight distinct
eye structures and T2 values in the vitreous humor.
These techniques can be applied to diagnose and/or
monitor response to existing or new therapies and/or
surgery in ocular diseases.
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