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Abstract #3471

Measurements of glutamatergic pathway in patients with schizophrenia using 7T MRSI

Yan Li 1 , Angela Jakary 1 , Daniel H Mathalon 2,3 , and Sarah J Nelson 1,4

1 Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States, 2 Department of Psychiatry, University of California San Francisco, San Francisco, California, United States, 3 Mental Health Service, San Francisco Veterans Administration Medical Center, San Francisco, California, United States, 4 Department of Bioengineering and Therapeutic Sciences, university of California San Francisco, San Francisco, California, United States

The purpose of this study was to compare the levels of glutamate, glutamine, γ-aminobutyric acid, glutathione and glycine in patients with schizophrenia to those in healthy controls using 3D short-echo MRSI at 7 Tesla.

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