Abstract #3575
Computed Diffusion-Weighted MR Imaging for Prostate Cancer Detection: Optimization of b-Value Combinations for Generating High b-Value Images.
Yoshiko Ueno 1 , Satoru Takahashi 1 , Kazuhiro Kitajima 1 , Yu Ueda 2 , Masamori Kassai 3 , Masao Yui 3 , Yoshiharu Ohno 1,4 , and Kazuro Sugimura 1
1
Department of Radiology, Kobe University
Graduate School of Medicine, Kobe, Hyogo, Japan,
2
Division
of Radiology, Kobe University Hospital, Kobe, Hyogo,
Japan,
3
MRI
Systems Development Department, Toshiba Medical Systems
Corp., Otawara, Tochigi, Japan,
4
Advanced
Biomedical Imaging Research, Kobe University Graduate
School of Medicine, Kobe, Hyogo, Japan
Computed DWI (cDWI) is proposed as a new technique that
produces any b-value images from DWIs acquired with at
least two different b-values. However, it remains
unclear which combination of b-values is optimal for
generating high-b-value images. We hypothesize that
appropriate b value selection for cDWI can improve image
quality and detection capability on cDWI as compared
with actual DWI with ultra-high b value. The aim of this
study was to determine the appropriate b-value
combination for generating cDWI at b=2000 s/mm
2
to
improve prostate cancer detection, when compared with
actual DWI at b=2000 s/mm
2
on
a 3T MR system.
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