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Abstract #3600

MR-VOLUMETRY OF THE LIVER AND THE SPLEEN IN CORRELATION TO LIVER IRON CONCENTRATION DETERMINED BY MRI-R2* AND BIOSUSCEPTOMETRY

Sarah Keller 1 , Bjrn Schnnagel 1 , Charlotte Pfeifer 1 , Zhiyue Jerry Wang 2 , Roland Fischer 3 , Christoph Berliner 1 , Moritz Brehmer 1 , Gerhard Adam 1 , and Jin Yamamura 1

1 Diagnostic and Interventional Radiology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany, 2 Department of Radiology, Children's Medical Center Dallas, Dallas, Tx, United States, 3 Department for Biochemistry, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany

Due to the increased iron stores, patients with iron overloading diseases eventually develop hepato- and splenomegaly. The purpose of this study was 1.) to investigate the accuracy of liver volumen measurements using MR-volumetry and ultasonic planimetry and 2.) to correlate liver volume with liver iron concentration assessed with MR-R2* relaxometry in patients with iron overloading diseases.

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