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Abstract #3625

The effect of cardiac phase on liver diffusion tensor imaging (DTI)

Oi Lei Wong 1,2 , Glady G Lo 3 , Raymond Lee 3 , Po Lung Polo Chan 3 , Wing Wa Li 3 , Siu Ki Yu 4 , and Michael D Noseworthy 5,6

1 Department of Medical Physics and Applied Radiation Science, McMaster University, Hamilton, Ontario, Canada, 2 Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong, Hong Kong, 3 Department of Diagnostic & Interventional Radiology, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong, 4 Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong, 5 Department of Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada, 6 St.Joseph's Healthcare, Hamilton, Ontario, Canada

Performing diffusion weighted imaging at the left liver lobe is often problematic due to regional signal loss. From the literature, the regional signal loss is possibly related to respiratory and cardiac motion. In this study, we studied the effect of cardiac phase, and hence motion, on liver DTI metrics, performed at various cardiac trigger delay settings. Significant change in DT metrics between systole and diastole was observed in the left liver lobe, but not the right liver lobe. This suggests that these metrics are sensitive to cardiac phase, and thus likely deformation.

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