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Abstract #3657

Non-invasive investigation of exocrine pancreatic function using cine dynamic MRCP with a spatially selective inversion-recovery (IR) pulse

KAUZUYA YASOKAWA 1 , AKIRA YAMAMOTO 1 , TSUTOMU TAMADA 1 , AKIHIKO KANKI 1 , ATSUSHI HIGAKI 1 , YASUFUMI NODA 1 , HIDEMITU SOTOZONO 1 , AYUMU KIDO 1 , AKANE UCHINO 1 , and KATSUYOSHI ITO 1

1 Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan

This study investigated whether cine dynamic MRCP with a spatially selective inversion recovery pulse can be used for evaluation of exocrine pancreatic functions in 10 patients with suspected chronic pancreatitis in comparison with currently available pancreatic exocrine function test with N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BT-PABA) reagent. The urinary PABA excretion rate (%) had significant positive correlations with both the mean secretion grade (the distance that the pancreatic juice moved in the pancreatic duct) and the frequency that the pancreatic juice flowed in the pancreatic duct. This technique has a potential to evaluate pancreatic exocrine function noninvasively in patients with suspected chronic pancreatitis.

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