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Abstract #3734

3D B0-adjusted and sensitivity-enhanced spectral localization by imaging (BASE-SLIM) of patients with gliomas

Peter Adany 1 , Phil Lee 1,2 , Sarah Taylor 3 , Roukoz Chamoun 4 , and In-Young Choi 1,5

1 Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States, 2 Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, United States, 3 Department of Internal Medicine, University of Kansas Medical Center, Westwood, KS, United States, 4 Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS, United States, 5 Neurology, University of Kansas Medical Center, Kansas City, KS, United States

An improved 3D non-Fourier based spectral localization technique is proposed providing further advancement from our previous advanced SLIM technique with simultaneous corrections for both B0 inhomogeneity and inhomogeneous coil sensitivity: B0-Adjusted and Sensitivity-Encoded (BASE)-SLIM. 3D BASE-SLIM provides reliable localization and improved spectral quality in any non-rectangular, arbitrary-shaped lesions or anatomical boundaries. The performance of 3D BASE-SLIM is demonstrated in the brain of patients with gliomas in three compartments: gray and white matter and lesions.

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