Meeting Banner
Abstract #3739

Easily implementable water signal scaling for 3D 1 H MR spectroscopic imaging in the human brain

Michal Bittsansky 1,2 , Petra Hnilicova 1 , Hubert Polacek 1,2 , and Dusan Dobrota 1

1 Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia, Slovakia, 2 Radiodiagnostic Clinic, Martin University Hospital, Martin, Slovakia, Slovakia

Our aim was to create a robust method for water scaling of 3D 1H MRSI in the brain, easily implementable in clinical conditions. For water referencing, we evaluated the performance of a 3D FID sequence with low pulse angles, short TR, and voxels corresponding to the metabolic spin-echo 3D MRSI sequence, at 1.5 Tesla using a phased-array coil with inhomogeneous sensitivity profile. We have shown the usefulness of this scaling method in a phantom, healthy volunteers and tumor patients. We were able to compare scaled metabolite signals between patients and between different brain areas, including tumors.

This abstract and the presentation materials are available to members only; a login is required.

Join Here