Sleep and Wakefulness Affect GABA Levels in the Dorsolateral Prefrontal Cortex
Luke Y.-J. Wang 1,2 , Sai K. Merugumala 2 , Huijun Liao 2 , and Alexander P. Lin 2
Department of Anesthesiology, Perioperative
and Pain Medicine, Boston Children's Hospital and
Harvard Medical School, Boston, MA, United States,
of Radiology, Brigham and Women's Hospital and Harvard
Medical School, Boston, MA, United States
Sleep and wakefulness are a complex yet distinct
physiological states. However, they are not generally
controlled for during brain spectroscopy. We report
higher detected levels of GABA during sleep, compared to
a controlled wakeful state.
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