Carnosine at 7T: quantification and relaxation times in m. gastrocnemius
Ivica Just Kukurova 1,2 , Martin Krk 1,3 , Marek Chmelik 1 , Martin Gajdok 1 , Siegfried Trattnig 1 , and Ladislav Valkovič 1,4
High-field MR Centre, Department of
Biomedical Imaging and Image-guided Therapy, Medical
University of Vienna, Vienna, Austria,
University of Technology, Bratislava, Slovakia,
of Endocrinology and Metabolism, Department of Internal
Medicine III, Vienna, Austria,
of Imaging Methods, Institute of Measurement Science,
Slovak Academy of Sciences, Bratislava, Slovakia
Carnosine in skeletal muscle plays an important role as
a buffer for intracellular pH. Its concentration can be
measured by proton MRS. Aim of this study was to measure
relaxation times of carnosine in m. gastrocnemius in
vivo at 7T which was achieved and succesfully applied
for quantification of concentration of carnosine.
Results will be used for further metabolic studies.
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