A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the pulmonary metastasis treatment.
Simonetta Geninatti 1 , Diego Alberti 2 , Antonio Toppino 2 , Annamaria Deagostino 2 , Stefania Lanzardo 2 , Nicoletta Protti 3 , Silva Bortulussi 3 , Saverio Altieri 3 , and Silvio Aime 2
Molecular Biotechnology and health sciences,
University of Torino, Torino, TO, Italy,
of Torino, TO, Italy,
of Pavia, PV, Italy
A new dual agent targeted to pulmunary metastasis via
Low Density Lipoprotein transporters has been proposed
as an efficient and selective carrier of Boron and
Gadolinium for MRI guided Boron Neutron Capture Therapy.
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