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Abstract #3999

Investigation of the influence of residual 1 H dipole-dipole couplings on magnetization transfer ratio maps of porcine menisci

Christina Hopfgarten 1 , Stefan Kirsch 1 , Gregor Reisig 2 , Michael Kreinest 2 , and Lothar R. Schad 1

1 Computer Assisted Clinical Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany, 2 Experimental Orthopaedics and Trauma Surgery, Orthopaedic and Trauma Center Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany

The aim of the experiments was to check, to which extend the MTR is affected by residual dipole-dipole couplings. Five porcine medial menisci were investigated. The transverse relaxation time shows a distinct variation of T2 values with the orientation of the imaged slice. In contrast, the MTR values are approximately constant over the all orientations. The observed absence of the magic angle (MA) effect in MTR maps may provide a useful tool for diagnosis of meniscal tissue degeneration since it prevents misinterpretation due to MA-artifacts.

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