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Abstract #4202

Multi-Phase Passband Cine SSFP: an fMRI technique with excellent spatiotemporal resolution at 7 Tesla

Zhongwei Chen 1,2 , Jing An 3 , Zhentao Zuo 1 , Rong Xue 1 , and Danny JJ Wang 4

1 State Key Laboratory of Brain and Cognitive Science,Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, Beijing, China, 2 Graduate School, University of Chinese Academy of Sciences, Beijing, Beijing, China, 3 Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, 4 Department of Neurology, University of California Los Angeles, Los Angeles, United States

Balanced SSFP is a promising fMRI technique due to its reduced susceptibility artifacts and high spatial and temporal resolution compared to GE-EPI. In this study, a novel multi-phase passband cine SSFP technique was introduced for event-related (ER) fMRI with a temporal resolution of 50 ms and spatial resolution of a few mm3. ER-fMRI experiment at 7T demonstrated that this technique can reliably detect the initial dip and can differentiate a time delay of 200ms in stimulus presentation. Multiphase passband SSFP is a promising fMRI technique at ultra high magnetic fields (7 Tesla).

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