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Abstract #4278

MP2RAGE in mice

Nathalie Just 1 , Olivier Reynaud 2 , and Rolf Gruetter 1,3

1 CIBM-AIT, EPFL, Lausanne, Switzerland, 2 Laboratory for functional and metabolic Imaging, EPFL, Lausanne, Switzerland, 3 Departments of Radiology, University of Lausanne and University of Geneva, Lausanne and Geneva, Switzerland

With the growing number of transgenic animal models of diseases, it is of paramount importance to develop high spatial resolution T1-weighted imaging techniques for structural imaging at ultra high fields. In the present work, the MP2RAGE technique was implemented at 14.1T and used to acquire T1-weighted images of a MnCl2-doped phantom and knockout mice. T1 mapping was also performed. The high translational value of MP2RAGE sequences was demonstrated.

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