Abstract #4320
10-Minute High-Resolution Whole-Brain T 1 Mapping: A Comparison of Three Candidate Methods
James A. Rioux 1 , Ives R. Levesque 1,2 , Manojkumar Saranathan 1 , and Brian K. Rutt 1
1
Radiology, Stanford University, Stanford,
CA, United States,
2
Medical
Physics, Oncology, and RI-MUHC, McGill University,
Montreal, QC, Canada
Three methods for whole-brain high-resolution T
1
mapping
are evaluated at 7T: 3-TI MPRAGE, MP2RAGE and MP3RAGE.
Each acquires a number of T
1
-weighted MPRAGE
images, allowing lookup of T
1
values
instead of a least-squares fit, and is B
1
-insensitive
to varying degrees. All acquisitions were matched at
10min total scan time and 1mm isotropic resolution.
MP2RAGE demonstrated the highest T
1
-to-Noise-Ratio,
while 3-TI MPRAGE had the lowest difference from a
reference map but has reduced T
1
NR due to the
acceleration required to achieve the desired scan time.
MP3RAGE is a good compromise method, with.higher T
1
NR
than 3-TI MPRAGE, but higher accuracy than MP2RAGE.
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