k-t-EPI: k-t-undersampled EPI acquisition and reconstruction in cerebral perfusion
Rebecca Ramb 1 , Elias Kellner 1 , Iulius Dragonu 1 , Frederik Testud 1 , Irina Mader 2 , Jrgen Hennig 1 , Maxim Zaitsev 1 , and Bernd Jung 1
Dept. of Radiology, Medical Physics,
University Medical Center, Freiburg, Baden-Wrttemberg,
of Neuroradiology, University Medical Center, Freiburg
Brain Imaging, Freiburg, Baden-Wrttemberg, Germany
Parallel imaging offers the potential to decrease
blurring and susceptibility artifacts in ssEPI
acquisitions by shortening echo train lengths, however,
at the expense of SNR. We propose k-t-EPI:
k-t-undersampled ssEPI acquisition with k-t-GRAPPA
reconstruction, in order to overcome SNR limitations.
The developed sequence with two acquisition strategies
and reconstruction is presented and applied in
first-pass cerebral perfusion measurements at reduction
factor R=4 and high spatial resolution. The gained
flexibility in increasing spatial and/or temporal
resolution by higher achievable reduction factors
requires further investigation, also in the context of
other applications such as diffusion or fMRI.
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