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Abstract #4462

Comparison of extended Point Spread Function and Reverse Gradient Polarity distortion corrections in quantification of DW EPI at UHF

Oleg Posnansky 1 , Myung-Ho In 1 , and Oliver Speck 1

1 Department of Biomedical Magnetic Resonance, Institute of Experimental Physics, Otto-von-Guericke University, Magdeburg, Germany

In this study, we compare fractional anisotropy (FA) maps and DT (diffusion tensor) fiber tracks built after application of extended PSF, and Reverse Gradient Polarity distortion correction methods. The results demonstrate that the extended PSF method is very efficient for the correction of distortions in both DW-EPI data with opposite PE polarity, and thus it unveils properly positioned and fully recovered fine anatomical structures in the brain FA maps and fiber tracks. Due to its high accuracy extended PSF provides overwhelming correspondence between anatomy and connectivity of the tissue.

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