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Abstract #4517

A method for evaluating the similarity of HARDI-based fiber tracking methods

Jian Lin 1 , Ken Sakaie 1 , Myron Zhang 2 , Katherine A Koenig 1 , Stephen E Jones 1 , and Mark J Lowe 1

1 Cleveland Clinic, Cleveland, OHIO, United States, 2 The Ohio State College of Medicine, OSU, Columbus, OHIO, United States

Tractography can be sensitive to a number of parameters. However, there are few methods for quantifying such sensitivity. We demonstrate a means for quantitative comparison of pathways by comparison with an ensemble of tracks. We apply the method to compare the results of two probabilistic tractography methods: a computationally intensive Monte Carlo (MC) approach and fast partial differential equations (PDE) that is designed to rapidly replicate the results of the MC approach.

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