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Abstract #4562

2-shim or not 2-shim, that is a question in pseudo continuous arterial spin labeling.

Wouter M Teeuwisse 1,2 , Sophie Schmid 1 , Michael Helle 3 , and Matthias van Osch 1

1 C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, ZH, Netherlands, 2 Leiden Institute for Brain and Cognition, Leiden, ZH, Netherlands, 3 Innovative Technologies, Research Laboratories, Philips Technologie GmbH, Hamburg, Germany

In pCASL, shimming the B0 field for optimal homogeneity is indispensable for optimal labeling efficiency and image quality. In this study the implementation of dual-shim pCASL, with separate shim settings for imaging and labeling, is evaluated. This approach is compared with pCASL with identical shim settings for imaging and labeling. Mean gray matter CBF and temporal SNR are calculated for left-, right- and posterior flow territories and left-right asymmetry is assessed. It is concluded that, when 1st order shimming is applied, application of separate shim settings during labeling does not result in significant changes in quantitative CBF or temporal SNR

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