Brainstem Cerebral Blood Flow in Women with Poly-Cystic Ovary Syndrome (PCOS)
Esther A. H. Warnert 1 , Andrew Lansdown 2 , Kevin Murphy 1 , Judith E. Hall 3 , D. Aled Rees 2 , and Richard G. Wise 1
CUBRIC, School of Psychology, Cardiff
University, Cardiff, United Kingdom,
for Endocrine and Diabetes Sciences, Institute of
Experimental and Molecular Medicine, School of Medicine,
Cardiff University, United Kingdom,
of Anaesthetics and Intensive Care Medicine, School of
Medicine, Cardiff University, United Kingdom
This abstract contains preliminary results of a clinical
study investigating brain function and physiology in
women suffering from Poly-Cystic Ovary Syndrome (PCOS).
Here, we focus on the brainstem (and the medulla in
particular), because of the recent finding that a
potential marker of PCOS is hyperactivity of the
sympathetic nervous system, in which nuclei in the
medulla play a central role. Arterial spin labelling is
used to assess differences in brainstem cerebral blood
flow between PCOS patients and healthy controls.
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