Evaluation of contrast agent dispersion in cerebral arteries using CFD simulations: influence on CBF quantification
Karsten Sommer 1 , Regine Schmidt 1 , Hanns-Christian Breit 1 , Dirk Graafen 1 , and Laura M. Schreiber 1
Department of Diagnostic and Interventional
Radiology, University Medical Center Mainz, Mainz,
In this contribution we present the CFD simulation of
contrast agent transport in a high detailed 3D model of
the cerebral arteries. We used the results of the
simulations to determine the errors induced by contrast
agent dispersion in cerebral blood flow quantification.
Contrary to recent studies, our results do not show
substantial contrast agent bolus dispersion.
Dispersion-related cerebral blood flow errors vary
between the different outlets of the 3D model, but are
on the whole much smaller than previously predicted.
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