Method of transforming brain spectroscopic waterline data into standard brain space (analyzing functional MRS in FSL)
Hamed Mojahed 1 , Fernando Arias-Mendoza 1 , and Truman R Brown 2
Columbia University, New York, NY, United
University of South Carolina, Charleston, SC, United
We present a method to register waterline spectroscopic
brain data to standard MNI brain for inter-subject
analysis. High spatial resolution non-water suppressed
3D EPSI data with CSF suppression inversion recovery
pulse was acquired from visual cortex during a
flickering checkerboard visual presentation. Principal
component analysis was performed on the resulting data.
1st PC score map was registered to high spatial
resolution structural MPRAGE. The transformation matrix
of this registration was applied to the 2nd PC score
map. MPRAGE was registered to standard brain and its
transformation matrix was applied to 1st or 2nd PC score
maps to enable group analysis.
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