Direct Comparison of Integrated PET-MRI and PET-CT FDG Quantification in the Dementia Population
Timothy Shepherd 1 , Bang-Bin Chen 2 , Kent Friedman 1 , Christopher Glielmi 3 , Thomas Koesters 1 , Kimberly Jackson 1 , Yu-Shin Ding 1 , David Faul 3 , and Fernando Boada 1
Bernard and Irene Schwartz Center for
Biomedical Imaging, Department of Radiology, New York
University School of Medicine, New York, NY, United
of Medical Imaging, National Taiwan University Hospital,
Healthcare, New York, NY, United States
Research indicates combining PET and MRI biomarkers of
Alzheimer's disease will provide better stratification
of patients with suspected dementia for clinical
diagnosis and monitoring of experimental therapies.
Integrated PET-MRI is ideally positioned to provide this
information simultaneously, but PET-MRI radiotracer
quantification is not trivial and its accuracy not
established. We report direct comparison of MRI- to
CT-based attenuation correction methods in the same
patients with suspected dementia.
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