Quantitative comparison of localized in vivo hepatic 31 P MRS at 7T.
Marek Chmelik 1 , Michal Povazan 1 , Martin Krk 1,2 , Stephan Gruber 1 , Ladislav Valkovic 1 , Siegfried Trattnig 1 , and Wolfgang Bogner 1
High Field MR Centre, Department of
Biomedical Imaging and Image-Guided Therapy, Medical
University of Vienna, Vienna, Austria, Austria,
of Endocrinology and Metabolism, Department of Internal
Medicine III, Medical University of Vienna, Austria
The feasibility of commonly used
localization techniques (1D-ISIS, 3D-ISIS, 2D CSI and 3D
CSI; n=9) that are suitable for both localized MRS of
focal lesions and semi-localized MRS for use in diffuse
pathologies in the human liver was demonstrated at 7T.
MRS at 7T provides improved data quality in acceptable
measurement time. All methods provided data with high
spectral quality regarding signal to noise, small
linewidth and low CRLB(<11%). Voxel volume and
acquisition time corrected SNR was similar for all the
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