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Abstract #0025

Steady-state Real-time Cine Imaging of Stress/Rest Myocardial Perfusion for Rapid Detection of High-grade Coronary Stenosis

Behzad Sharif 1 , Reza Arsanjani 1 , Hsin-Jung Yang 1 , Rohan Dharmakumar 1 , Noel Bairey Merz 1 , Daniel S. Berman 1 , and Debiao Li 1

1 Biomedical Imaging Research Institute, Dept. of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, United States

We present a multi-slice cine first-pass perfusion imaging method capable of simultaneous detection of stress-induced myocardial perfusion defects and wall motion abnormalities in a single ungated scan using a 1-minute continuous acquisition. Our initial results in ischemic canines demonstrate that worsening of wall motion (compared to rest) in the perfusion defect territories seen in the real-time stress cine perfusion scan may be a marker of severe (high grade) coronary artery disease.

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