Steady-state Real-time Cine Imaging of Stress/Rest Myocardial Perfusion for Rapid Detection of High-grade Coronary Stenosis
Behzad Sharif 1 , Reza Arsanjani 1 , Hsin-Jung Yang 1 , Rohan Dharmakumar 1 , Noel Bairey Merz 1 , Daniel S. Berman 1 , and Debiao Li 1
Biomedical Imaging Research Institute, Dept.
of Biomedical Sciences, Cedars-Sinai Medical Center, Los
Angeles, California, United States
We present a multi-slice cine first-pass perfusion
imaging method capable of simultaneous detection of
stress-induced myocardial perfusion defects and wall
motion abnormalities in a single ungated scan using a
1-minute continuous acquisition. Our initial results in
ischemic canines demonstrate that worsening of wall
motion (compared to rest) in the perfusion defect
territories seen in the real-time stress cine perfusion
scan may be a marker of severe (high grade) coronary
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