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Abstract #0114

Correlation between Cartilaginous endplate defects and Intervertebral disc degeneration: An In Vivo MRI Study at 3.0 Tesla

Dong Xing 1 , Jiao Wang 1 , Yunfei Zha 1 , Lei Hu 1 , Hui Lin 2 , and Yuan Lin 1

1 Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China, 2 GE Healthcare China, Shanghai, China

Although IVDD is a multifactorial disease, it is well accepted that limited nutrition is the final common pathway for IVDD and the changes in the structure or composition of the cartilaginous endplate (CEP) have been considered a crucial role in IVDD. The ultrashort echo time (UTE) sequence has been used in detecting the CEP defects and the visual classification of IVDD , however, a further study utilized the quantitative parameter of T2*-relaxation time would be benefit to understand the causes of disc degeneration of early stage. The purpose of this study was to use 3D-UTE and T2*- mapping sequence to ascertain the relation between CEP Integrity and IVDD.

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