Abstract #0192
In vivo cross-validation study of contrast kinetic model analysis with simultaneous B 1 /T 1 estimation
Jin Zhang 1,2 , Kerryanne Winters 1,2 , and Sungheon Gene Kim 1,2
1
Center for Advanced Imaging Innovation and
Research (CAI2R), Dept. Radiology, NYU School of
Medicine, New York, NY, United States,
2
Bernard
and Irene Schwartz Center for Biomedical Imaging, Dept.
Radiology, NYU School of Medicine, New York, NY, United
States
In our previous studies, we introduced Active-Contrast
Encoding MRI (ACE-MRI) which measures both B
1
and
T
1
values
along with kinetic parameters from a single DCE-MRI
data. The model free approach of ACE-MRI we proposed
separates estimation of B
1
/T
1
from
estimation of contrast kinetic parameters, and
consequently improves parameter estimation accuracy and
precision. This in vivo cross-validation study was
conducted to compare the contrast kinetic parameters
estimated from ACE-MRI data with those estimated from
conventional DCE-MRI experiments with separate
measurements of B
1
and
T
1
.
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