Prospective motion correction for artefact reduction in pseudo-continuous arterial spin labelling with a 3D GRASE readout.
Benjamin Knowles 1 , Federico von Samson-Himmelstjerna 2,3 , Matthias Guenther 2,4 , and Maxim Zaitsev 1
Medical Physics, University Medical Centre,
Mevis, Bremen, Germany,
Medical University, Center for Stroke Research, Berlin,
of Bremen, Germany
Arterial spin labelling (ASL) is a non-invasive method
to measure blood perfusion. One limitation to ASL is
that motion is highly corruptive, and leads to errors in
perfusion-weighted images. This is especially
problematic for 3D. In this study, the effectiveness of
prospective motion correction (PMC) with an optical
camera for artefact reduction in a pseudocontinuous ASL
sequence with a 3D GRASE readout is investigated. Data
are acquired using single-shot and segmented techniques.
Segmented readouts are found to be strongly improved
with PMC, even for compliant subjects. For single-shot,
an intra-readout correction may still be required.
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