T1ρ and T2-based quantitative technique for characterization of regional variations in intervertebral discs to detect early degenerative changes.
Prachi Pandit 1 , Martin Kretzschmar 1 , Valentina Pedoia 1 , William Dillon 1 , and Sharmila Majumdar 1
Radiology and Biomedical Imaging, University
of California San Francisco, San Francisco, CA, United
Regional variation of T1p and T2 values within the
nucleus pulposa (NP) and annulus fibrosa (AF) of
intervertebral discs (IVDs) has the potential of being a
powerful biomarker for degenerative disc disease (DDD),
much more so than just their mean values.
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