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Abstract #0439

Simultaneous Quantitative Mapping of T 1 , T 2 *, and Magnetic Susceptibility with Multi-Echo MP2RAGE at 7 T

Riccardo Metere 1 , Harald E. Mller 1 , Gunnar Krger 2,3 , Tobias Kober 2,3 , and Andreas Schfer 1

1 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2 Siemens ACIT CHUV Radiology, Siemens Healthcare IM BM PI & Department of Radiology CHUV, Lausanne, Switzerland, 3 LTS5, cole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland

Knowledge of the relaxation times is essential for understanding the biophysical mechanisms underlying image contrast, and can be related to tissue composition. Quantitative experiments are essential for cross-study comparisons, but often require longer acquisition times. Using the prototype Multi-Echo (ME) MP2RAGE pulse sequence, we show the possibility of obtaining reliable T 1 , T 2 *, and magnetic susceptibility maps that are inherently co-registered. The acquisition time required for such experiments is comparable to the time required for T 1 map acquisition with MP2RAGE. This result is obtained as a trade-off between resolution and the parameters of the multi-echo readouts.

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