Abstract #0473
Localizing and characterizing single fiber populations throughout the brain
Chantal M.W. Tax 1 , Dmitry S. Novikov 2 , Eleftherios Garyfallidis 3 , Max A. Viergever 1 , Maxime Descoteaux 3 , and Alexander Leemans 1
1
Image Sciences Institute, University Medical
Center Utrecht, Utrecht, Utrecht, Netherlands,
2
Center
for Biomedical Imaging, New York University School of
Medicine, New York, New York, United States,
3
Sherbrooke
Connectivity Imaging Lab, Universit de Sherbrooke,
Sherbrooke, Quebec, Canada
In this work we localize single fiber population (SFP)
voxels in the brain by recursively excluding crossing
fiber voxels with constrained spherical deconvolution in
multi-shell diffusion MRI data. We investigate the
average signal decay over all SFPs parallel and
perpendicular to the fiber, and extract
(microstructural) diffusion indices by fitting various
models. By doing so, we have characterized SFPs
throughout the brain and in different tracts, which can
potentially be used as reference for healthy brain in
group studies or simulation studies.
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