18F-FDG and 18F-NaF PET/MR Imaging of Osteoarthritis in the Knee: Considerations and Initial Results
Feliks Kogan 1 , Audrey Fan 1 , Sloane Brazina 1 , Dawn Holley 1 , Andrew Quon 1 , and Garry Gold 1
Department of Radiology, Stanford
University, Stanford, CA, United States
New hybrid PET/MR systems allow for simultaneous,
sensitive, and quantitative assessments of early bone
activity in osteoarthritis (OA) with PET, which can be
correlated with high-resolution quantitative MR methods
of other tissues to study the pathogenesis of OA We
demonstrate initial results of simultaneous
time-of-flight PET/MR hybrid imaging of the knee OA.
Results suggest that PET/MR may detect knee
abnormalities unseen on MRI alone and is a promising
tool for early detection of OA change in the bone.
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