Abstract #0518
Intracranial atherosclerotic lesion characteristics correlate with cerebrovascular lesion load after TIA or ischemic stroke: a 7.0 tesla MRI study
Nikki Dieleman 1 , Anja G. van der Kolk 1 , Jaco J.M. Zwanenburg 1,2 , Manon Brundel 3 , Anita A. Harteveld 1 , Geert Jan Biessels 3 , Fredy Visser 1,4 , Peter R. Luijten 1 , and Jeroen Hendrikse 1
1
Radiology, University Medical Center
Utrecht, Utrecht, Utrecht, Netherlands,
2
Image
Science Institute, University Medical Center Utrecht,
Utrecht, Netherlands,
3
Neurology,
University Medical Center Utrecht, Utrecht, Netherlands,
4
Philips,
Best, Netherlands
In this prospective study we investigated the presence
of cortical microinfarcts (CMIs) at 7.0 tesla MRI in
patients with a transient ischemic attack or ischemic
stroke of the anterior circulation and explored the
relationship between intracranial atherosclerosis
(ICAS), CMIs and macroinfarcts. This study shows that in
CMIs represent a relevant portion of the total
cerebrovascular lesion load and coexist with
macroinfarcts. Furthermore, specific ICAS
characteristics correlate with a higher cerebrovascular
lesion load suggesting that ICAS may be a shared
etiology. These results shine new light on the spectrum
of parenchymal damage caused by ICAS.
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