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Abstract #0600

Simultaneous multi-slice functional CBV measurements at 7 T

Laurentius Huber 1 , Dimo Ivanov 2 , Maria Guidi 1 , Robert Turner 1 , Kmil Uluda─č 2 , Harald E Mller 1 , and Benedikt A Poser 2

1 Max Planck Institute for Human Cognitive & Brain Sciences, Leipzig, Germany, 2 Maastricht Brain Imaging Centre, Netherlands

In this study, we combined high-field (7 T) VASO with a simultaneous-multi-slice (SMS) acquisition scheme. We implemented and evaluated this method for simultaneous acquisition of functional changes in cerebral blood volume and BOLD signal at high spatial resolution, using a visuo-motor task, and covering a large number of brain areas including V1, V5, M1, and S1. We show that SMS-VASO can measure blood volume changes with high spatial resolution and satisfactory CNR, across multiple brain regions and with better local specificity than GE-BOLD signal.

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