Abstract #0602
Functional Pathways in Monkey Brain Mapped Using Resting State Correlation Tensors
Tung-Lin Wu 1 , Feng Wang 1,2 , Li Min Chen 1,2 , Adam W. Anderson 1,2 , Zhaohua Ding 1,2 , and John C. Gore 1,2
1
Vanderbilt University Institute of Imaging
Science, Nashville, TN, United States,
2
Radiology
and Radiological Sciences, Vanderbilt Univeristy,
Nashville, TN, United States
Recently, we reported that anisotropic correlations
between resting state signals within a local region of
white matter can be used to drive functional structures
that closely resemble DTI data but without the use of
diffusion gradients. Indeed, we demonstrated a technique
that delineates the functional architecture of the
brain, especially white matter, purely on the basis of
fMRI data. In order to explore and verify the
biophysical mechanisms for the observed spatio-temporal
correlations in white matter signals, we carried out
imaging studies on live anesthetized squirrel monkeys
and compared spatio-temporal correlation tensors from
T2* and cerebral blood volume (CBV)-weighted fMRI.
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