Abstract #0672
Evaluation of Stretched-Exponential Model for Diffusion-Weighted Imaging of breast lesions Using High b Values: comparison with monoexponential Diffusion Weighted Imaging
Chunling Liu 1 , Changhong Liang 1 , Yingjie Mei 2 , Zaiyi Liu 1 , and Jine Zhang 1
1
Department of Radiology, Guangdong General
Hospital/Guangdong Academy of Medical Sciences,
Guangzhou, Guangdong, China,
2
Philips
Healthcare, Guangzhou, Guangdong, China
Breast cancer is the most commonly diagnosed type of
cancers of women. In this study, we obtained the
parameters (ADCs and ) information using a
stretched-exponential model with high b-values for
normal breast and breast lesions and compared them to
apparent diffusion coefficient (ADC) with conventional
DWI in their ability to discriminate benign lesions and
malignant tumors. 77 patients underwent a standard
bilateral breast MRI examination including DWI sequence
and ADCs, and ADC were obtained according to
different diffusion models. The statistical analysis
results suggest that ADCs of the stretched model can be
used to differentiate benign and malignant lesions and
has the highest specificity, comparing the conventional
ADC, however, is not different between benign and
malignant tumors and may be further investigated.
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