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Abstract #0688

Diffusion Imaging Of Head And Neck At High Angular And Spatial Resolution Using Multi-Shot Spirals

Merry Mani 1 , Mathews Jacob 2 , and Vincent Magnotta 3

1 Dept of Psychiatry, University of Iowa, Iowa City, IA, United States, 2 Dept of Electrical and Computer Engineering, University of Iowa, Iowa City, IA, United States, 3 Dept of Radiology, University of Iowa, Iowa City, IA, United States

Brain regions such as pons, cerebellum, spine etc are difficult to image using diffusion imaging due to the presence of air/bone/tissue interfaces causing severe susceptibility artifacts. In addition, cardiac pulsation, respiratory and swallowing motions also adversely affect these regions. We present a high spatial and angular resolution diffusion scheme that can image these regions without being severely corrupted by these artifacts. The proposed method uses a compressed sensing based joint k-q space under-sampling using multi-shot variable density spirals to image these regions. The motion-compensated joint reconstruction can recover diffusion orientation distribution functions at high resolution to enable the study of these regions.

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