Endogenous assessment of chronic myocardial infarction with T1 -mapping in patients
Joep van Oorschot 1 , Hamza El Aidi 1 , Fredy Visser 2 , Pieter Doevendans 1 , Peter Luijten 1 , Tim Leiner 1 , and Jaco Zwanenburg 1
University Medical Center Utrecht, Utrecht,
Healthcare, Best, Noord-Brabant, Netherlands
Studies in animal models have shown that cardiac
T1ρ-mapping can be used to detect myocardial fibrosis
without the use of a contrast agent. In this study we
performed cardiac T1ρ-mapping for detection of chronic
MI in 21 patients, and compared it with the LGE method.
A significantly higher T1ρ relaxation time was found in
the infarct region (79 11 ms), compared to healthy
remote myocardium (55 6 ms). A sensitivity of 0.77 and
a specificity of 0.73 was found for T1ρ-mapping compared
to LGE imaging.
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