Carotid Atherosclerotic Plaque Surface Condition Evaluation Utilizing Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP) Sequence
Shuo Chen 1 , Xihai Zhao 1 , Niranjan Balu 2 , Haining Liu 2 , Zechen Zhou 1 , Jinnan Wang 2,3 , Rui Li 1 , Chun Yuan 1,2 , and Huijun Chen 1
Center for Biomedical Imaging Research,
Department of Biomedical Engineering, School of
Medicine, Tsinghua University, Beijing, Beijing, China,
of radiology, University of Washington, Seattle, United
Research North America, Briarcliff Manor, NY, United
In carotid atherosclerotic plaque, surface conditions
such as juxtaluminal calcification (JCA) and ulceration
are believed to be linked to plaque vulnerability.
Conventionally, multi-contrast sequences (T1w-TSE,
T2w-TSE, 3D TOF) are used to determine the plaque
components and vulnerability. However, conventional
multi-contrast is constrained by limited longitudinal
coverage, long acquisition time and inter-scan motion.
Recently, a simultaneous non-contrast angiography and
intraplaque hemorrhage (SNAP) sequence was proposed for
carotid artery imaging. In this work, we sought to
evaluate the feasibility of carotid plaque surface
condition evaluation using SNAP sequence alone.
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