Temporal-Variance Weighted P-space Multipole Frequency Mapping
Kyle S Decker 1,2 and Chunlei Liu 3,4
Center for In Vivo Microscopy, Duke
University, Durham, NC, United States,
Engineering, Duke University, Durham, NC, United States,
Imaging and Analysis Center, Duke University, Durham,
NC, United States,
Duke University, Durham, NC, United States
Through the use of improved processing methods, we are
able to use a single-shift p-space image reconstruction
to produce high fidelity multipole frequency maps using
multi-echo data. The temporal-variance of higher-order
multipole frequency distribution is dominant in the
white matter (WM), thus allowing the use of
temporal-variance to enhance multipole frequency maps of
WM in the p-space. This method suppresses artifacts in
isotropic regions including gray matter and allows
isolated characterization of sub-voxel WM anisotropy.
The resulting temporal-variance weighted p-space
multipole frequency maps provide a new contrast
mechanism with enhanced WM anisotropy and contrast.
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