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Abstract #0926

iLSQR: a Quantitative Susceptibility Mapping method Provided by STI Suite V2.12

Wei Li 1,2 , Nian Wang 3 , Bing Wu 4 , Timothy Q. Duong 1 , and Chunlei Liu 3,5

1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States, 2 Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States, 3 Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, 4 GE Healthcare, Beijing, China, 5 Radiology, Duke University, Durham, NC, United States

A novel method, namely iLSQR, is developed for quantitative susceptibility mapping. This method uses the previously developed LSQR method to derive an initial mapping of magnetic susceptibility, a fast quantitative susceptibility mapping method to estimate the susceptibility boundaries, and an iterative approach to estimate and remove the susceptibility artifact using ill-conditioned k-space regions only. With a fixed set of parameters, this iLSQR method provides effective elimination of streaking artifacts, unbiased quantification of magnetic susceptibility as compared to COSMOS, and robustness over a range of spatial resolutions. This method is provided in the software package of STI Suite v2.12.

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