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Abstract #0934

Bone Marrow Fat Quantification in calcaneus. Why not?

Silvia Capuani 1,2 , Giulia Di Pietro 2,3 , Guglielmo Manenti 4 , Vincenzo Vinicola 5 , Marco Bozzali 6 , and Umberto Tarantino 7

1 Physics Department, CNR-IPCF Roma Sapienza University of Rome, Rome, Italy, Italy, 2 Center for Life NanoScience@LaSapienza, Istituto Italiano di Tecnologia, Rome, Italy, Italy, 3 Enrico Fermi Center, Rome, Italy, Italy, 4 Department of Diagnostic Imaging and Interventional Radiology, Tor Vergata University of Rome, Rome, Italy, Italy, 5 4Rehabilitation Hospital IRCCS Santa Lucia Foundation, Rome, Italy, Rome, Italy, Italy, 6 Neuroimaging Laboratory Santa Lucia Foundation, Rome, Italy, Italy, 7 5Department of Orthopaedics and Traumatology, PTV Foundation, Tor Vergata University of Rome, Rome, Italy, Italy

The investigation of calcaneus bone-marrow might offer the chance of reducing the risk of subjects claustrophobic reactions, which remains a major source of drop-outs in Magnetic Resonance (MR) examinations. In this work the reliability and the potential of MR Spectroscopy in calcaneus is discussed. MRS in calcaneus can provide reliability fats estimation and L13/L43, L13/L52+L53 may be reliable markers of osteoporosis. Since bone-marrow fats in calcaneus are characterized by a different metabolism compared to that of vertebral or femoral sites, MRS in calcaneus performed in large population, may increase our pathophysiological understanding of osteoporosis from a metabolic point of view.

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